How many hours should you wait before taking more ibuprofen

Ibuprofen is a type of nonsteroidal anti-inflammatory drug (NSAID). It’s typically taken to help ease symptoms like pain, inflammation, and fever.

Ibuprofen is sold under the brand names Advil, Motrin, and Midol, among others.

This drug works by inhibiting an enzyme that helps produce compounds called prostaglandins. Prostaglandins are associated with pain and inflammation in the body.

But how long do the effects of ibuprofen take to work? And what dosage is both safe and effective?

Generally it takes about 30 minutes for you to begin feeling the effects of ibuprofen. However, this timeframe can vary from one person to the next, and for different reasons.

When ibuprofen begins to work, you’ll typically start to notice a decrease in pain or fever. The anti-inflammatory effects of ibuprofen usually take longer — sometimes a week or more.

Ibuprofen levels in your bloodstream are estimated to be at their maximum level after 1 to 2 hours.

However, ibuprofen is quickly cleared from your body. This is one of the reasons why — depending on the condition that’s being treated — you may need to take a dose every few hours.

The timing of ibuprofen levels appear to be similar in children. Younger children may clear ibuprofen from their system faster than adults.

Some people may experience symptom relief quickly while others find that it takes longer. This is because various factors can impact how long a drug takes to work.

Some factors that may affect how quickly ibuprofen takes to work for you include:

  • the dosage that’s taken
  • your weight
  • your age
  • your overall health
  • if you have food in your stomach
  • whether or not other drugs are taken at the same time

Over-the-counter (OTC) ibuprofen is typically available in 200-milligram (mg) pills.

It’s best to use the minimum dosage necessary to relieve your symptoms. Typically, one ibuprofen pill is taken by mouth every 4 to 6 hours. If one pill doesn’t work to ease symptoms, a second pill can be taken.

Don’t take more than 1,200 mg of ibuprofen in one day. For OTC ibuprofen, this equates to a maximum of 6 pills per day.

Additionally, avoid taking ibuprofen for longer than 10 days, unless directed to do so by your doctor.

A common side effect of ibuprofen and other NSAIDs is an upset stomach. Because of this, it may be helpful to take ibuprofen with food or milk.

Dosage for children

Ibuprofen can be given to children as a liquid solution, chewable tablet, or pill. Which form is recommended will depend on the child’s age.

The dosage of ibuprofen in children under age 12 is based on the child’s body weight.

If your child needs to take ibuprofen, ask their pediatrician for the recommended dosage and how often it needs to be taken.

Ibuprofen isn’t the only type of NSAID available. There are other options you can try if you’re unsure about taking ibuprofen.

In addition to ibuprofen, aspirin and naproxen (Aleve) are also available over the counter. Remember that aspirin should never be given to children and adolescents due to the risk of Reye’s syndrome.

Some NSAIDs are only available with a prescription. A few examples of these include:

  • celecoxib (Celebrex)
  • diclofenac (Voltaren)
  • feneoprofen (Nalfon)
  • indomethacin (Indocin)
  • ketorolac (Toradol)

If you’re not sure which NSAID is right for you, talk to your doctor. Based on your medical history and current medications, your doctor can recommend an NSAID that’s safe and appropriate for you to take.

Ibuprofen can be taken to help ease symptoms like pain, inflammation, and fever.

While the amount of time it takes for ibuprofen to work can vary, it usually takes about half an hour to start feeling symptom relief.

Adults can take a dose of OTC ibuprofen every 4 to 6 hours. When taking ibuprofen, be sure not to exceed the maximum daily dosage or to take it for more than 10 days. Dosing for children depends on body weight.

Ibuprofen may not be recommended if you have certain health conditions or are taking specific medications. If you have questions or concerns about taking ibuprofen, speak with your doctor.

QUESTION & ANSWER Q: How often can you take 800 mg ibuprofen?

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A:

The maximum daily dosage of ibuprofen is 3200 mg. This translates to 800 mg four times a day, taken every six hours. If stomach upset occurs, take each ibuprofen dose with milk or food. In general, it’s best to use the lowest effective dose of ibuprofen for the shortest duration of time.

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About The Author

Sarah Lewis, PharmD Healthgrades Medical Writer

Sarah Lewis is a pharmacist and a medical writer with over 25 years of experience in various areas of pharmacy practice. Sarah holds a Bachelor of Science in Pharmacy degree from West Virginia University and a Doctor of Pharmacy degree from Massachusetts College of Pharmacy. She completed Pharmacy Practice Residency training at the University of Pittsburgh/VA Pittsburgh Healthcare System. 

Last Updated: February 13, 2020

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Never ignore professional medical advice in seeking treatment because of something you have read on the site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

View Sources

  1. Ibuprofen (Oral Route). Mayo Foundation for Medical Education and Research. https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/description/drg-20070602 
  2. Ibuprofen Prescribing Information. Drugs.com. https://www.drugs.com/pro/ibuprofen.html 

Can I take more ibuprofen after 3 hours?

If you take ibuprofen 3 times a day, leave at least 6 hours between doses. If you take it 4 times a day, leave at least 4 hours between doses. If you have pain all the time, your doctor may recommend slow-release ibuprofen tablets or capsules. You'll usually take these once a day in the evening or twice a day.

Can you take 3 ibuprofen 200mg at once?

To avoid the potential short- or long-term effects of taking too much ibuprofen, do not take more than your recommended dose. The absolute maximum daily dose for adults is 3200 mg. Do not take more than 800 mg in a single dose. Only use the smallest dose needed to alleviate your swelling, pain, or fever.

Can I take 600 mg of ibuprofen every 4 hours?

Take 600-800mg of Ibuprofen (Advil) every 4-6 hours as needed for pain. If additional pain relief is needed, take 1000mg of Tylenol with the Ibuprofen every 4-6 hours as needed.

Can I take more ibuprofen after 6 hours?

Adults and teenagers—400 milligrams (mg) every four to six hours, as needed. Children over 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose usually is 10 milligrams (mg) per kilogram (kg) of body weight every six to eight hours, as needed, up to 40 mg per kg per day.