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This content is intended for U.S. Healthcare Professionals. Would you like to proceed? If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents. Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information. Both the 1 mL vial and the 1 mL prefilled syringe of Depo-Provera CI should be vigorously shaken just before use to ensure that the dose being administered represents a uniform suspension. The recommended dose is 150 mg of Depo-Provera CI every 3 months (13 weeks)
administered by deep intramuscular (IM) injection using strict aseptic technique in the gluteal or deltoid muscle, rotating the sites with every injection. As with any IM injection, to avoid an inadvertent subcutaneous injection, body habitus should be assessed prior to each injection to determine if a longer needle is necessary particularly for gluteal IM injection. Use for longer than 2 years is not recommended (unless other birth control methods are considered inadequate) due to the
impact of long-term Depo-Provera CI treatment on bone mineral density (BMD) [see Warnings and Precautions (5.1)]. Dosage does not need to be adjusted for body weight [see Clinical Studies (14.1)]. To ensure the
patient is not pregnant at the time of the first injection, the first injection should be given ONLY during the first 5 days of a normal menstrual period; ONLY within the first 5-days postpartum if not breast-feeding; and if exclusively breast-feeding, ONLY at the sixth postpartum week. If the time interval between injections is greater than 13 weeks, the physician should determine that the patient is not pregnant before administering the drug. The efficacy of Depo-Provera CI depends on
adherence to the dosage schedule of administration. When switching from other contraceptive methods, Depo-Provera CI should be given in a manner that ensures continuous contraceptive coverage based upon the mechanism of action of both methods, (e.g., patients switching from oral contraceptives should have their first injection of Depo-Provera CI on the day after the last active tablet or at the
latest, on the day following the final inactive tablet). Did you find an answer to your question? Yes No OverviewDepo-Provera is a well-known brand name for medroxyprogesterone acetate, a contraceptive injection that contains the hormone progestin. Depo-Provera is given as an injection every three months. Depo-Provera typically suppresses ovulation, keeping your ovaries from releasing an egg. It also thickens cervical mucus to keep sperm from reaching the egg. Medroxyprogesterone acetate is also available in a lower dosage. This version is called Depo-SubQ Provera 104. While Depo-Provera is injected deep into the muscle, Depo-SubQ Provera 104 is injected just beneath the skin. Depo-Provera and Depo-SubQ Provera 104 have similar benefits and risks. To use Depo-Provera or Depo-SubQ Provera 104, you'll need to visit your doctor or other health care provider. Why it's doneDepo-Provera is used to prevent pregnancy and manage medical conditions related to your menstrual cycle. Your health care provider might recommend Depo-Provera if:
Among various benefits, Depo-Provera:
Depo-Provera isn't appropriate for everyone, however. Your health care provider might discourage use of Depo-Provera if you have:
In addition, tell your health care provider if you have diabetes, uncontrolled high blood pressure or a history of heart disease or stroke, and unexplained vaginal bleeding. RisksIn a year of typical use, an estimated 6 out of 100 people using Depo-Provera will get pregnant. But the risk of pregnancy is much lower if you return every three months for your injection. Depo-SubQ Provera 104 was highly effective in initial studies. However, it's a newer medication, so current research may not reflect pregnancy rates in typical use. Among the things to consider about Depo-Provera are:
Other side effects of Depo-Provera usually decrease or stop within the first few months. They might include:
Consult your health care provider as soon as possible if you have:
Many experts believe progestin-only contraceptive methods, such as Depo-Provera, carry significantly lower risks of these types of complications than do contraceptive methods that contain both estrogen and progestin. How you prepareYou'll need a prescription for Depo-Provera from your health care provider, who will likely review your medical history and possibly check your blood pressure before prescribing the drug. Talk to your health care provider about all your medications, including nonprescription and herbal products. If you want to give yourself Depo-Provera injections at home, ask your health care provider if that's an option. What you can expectTo use Depo-Provera:
Feb. 22, 2022 Depo-Provera (contraceptive injection)
Can Depo be self administered?Self-administration of DMPA-SC is safe and effective and might expand access to a user-controlled contraceptive method.
How do you give yourself a DepoPinch the skin around the chosen injection site. Push the small needle all the way into the skin at about a 45-degree angle and inject the Depo slowly, over 5 to 7 seconds (Picture 3). Make sure to push the plunger all the way down and inject the medicine completely under the skin. Remove the needle from the skin.
When can I give myself the Depo shot?The first injection of Depo-Provera® is usually given within the first seven days of the start of your menstrual period. However, it can be given at another time if you and your healthcare provider are confident that you aren't pregnant. Your provider may have you take a pregnancy test before getting the shot.
Who can inject Depo?Depo is injected by a doctor or nurse into the arm or bottom muscle every 12-14 weeks.
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