Coricidin chest congestion and cough drug interactions

Coricidin chest congestion and cough drug interactions

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CORICIDIN HBP CHEST CONG-COUGH (Generic for ALKA-SELTZER PLUS MUCUS-CONGES) Lifestyle Interactions

Dextromethorphan Hydrobromide 10mg, Guaifenesin 200mg, Oral capsule, liquid filled

Grapefruit juice

· Severity: Mild

· Notes for Consumers: Grapefruit juice may increase the actions of Dextromethorphan, which may make some people feel drowsiness or other side effects (dizziness, nervousness or restlessness, nausea, vomiting, stomach upset) of Dextromethorphan that do not usually occur with prescribed or nonprescription product doses. It may be best to limit intake of grapefruit juice while you are taking Dextromethorphan-containing products.

· Notes for Professionals: Intake of grapefruit juice or seville orange juice increased dextromethorphan bioavailability in one study. Patients with increased concentrations of dextromethorphan may experience drowsiness or serotonergic side effects (dizziness, nervousness or restlessness, nausea, vomiting, stomach upset) not usually noted with prescribed or nonprescription product doses. Grapefruit juice and seville orange juice contain compounds that can inhibit P-glycoprotein in the intestinal wall, and dextromethorphan absorption may be affected by P-glycoprotein activity. Dextromethorphan is largely metabolized by CYP2D6, so this particular interaction with grapefruit juice may be more relevant in patients who are poor CYP2D6 metabolizers.

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Published: Dec 28, 2018 Last Updated: Oct 28, 2019

They are safe to take together. There is no known interaction.

Coricidin chest congestion and cough drug interactions

Dec 20, 2018

Sue asked

Can I take Tylenol with Coricidin HBP Chest Congestion And Cough?

At a glance

  • Tylenol (acetaminophen) and Coricidin HBP Chest Congestion And Cough (Dextromethorphan; Guaifenesin) are safe to take together.

Answer

Coricidin chest congestion and cough drug interactions

Tylenol (acetaminophen) can safely be taken with Coricidin HBP Chest Congestion And Cough, which contains the following active ingredients:

  • Guaifenesin
  • Dextromethorphan

There are no known interactions between these three drugs.

In fact, there are a variety of products available over the counter (OTC) that contain all three, or more. Such products include:

  • DayQuil Severe (Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine)
  • Tylenol Cold And Flu Severe (Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine)

As you are inquiring about a Coricidin HBP product specifically, I assume that you are looking for something that is safe to take if you have high blood pressure.

If you do have high blood pressure, you generally want to avoid nasal decongestants, like Sudafed (pseudoephedrine) and Sudafed PE (phenylephrine). These drugs can increase blood pressure and may put you more at risk for heart attack and stroke if your high blood pressure is untreated or uncontrolled.

Drug Info

The 2 products in your question (Tylenol & Coricidin HBP Chest Congestion And Cough) should not affect blood pressure at all. To give a quick overview of each:

  • Acetaminophen

Pain reliever and fever reducer. Acetaminophen is the most common analgesic used in combination ingredient cough/cold products. It is important to keep track of your daily acetaminophen consumption, especially if taking more than one product that contains it. Recommended doses are generally safe and effective but overdoses can lead to liver damage.

  • Guaifenesin

Thins and loosens mucus secretions. This allows for easier expectoration. Guaifenesin, which is also the active ingredient in Mucinex, is very well tolerated and actually has no known drug interactions.

  • Dextromethorphan

Cough suppressant, which is also the active ingredient in Delsym.

References
  • Coricidin Manufacturer Site

  • Tylenol Manufacturer Site

  • Clinical Key Drug Monograph

Coricidin chest congestion and cough drug interactions

Dr. Brian Staiger Pharm.D

Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010.

He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs.

Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours!

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Does Coricidin interact with any medications?

Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine during treatment with this medication.

Who should not take Coricidin?

You should not use Coricidin if you are allergic to acetaminophen or chlorpheniramine, or if you have: severe constipation, blockage in your stomach or intestines; untreated or uncontrolled diseases--glaucoma, asthma, heart disease, overactive thyroid; or. if you are unable to urinate.

What drugs should not be taken with dextromethorphan?

do not take dextromethorphan if you are taking a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking an MAO inhibitor within the past 2 weeks.

Can you take Tylenol when taking Coricidin?

Interactions between your drugs No interactions were found between Coricidin HBP Chest Congestion & Cough and Tylenol. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.